We calculated pooled effect estimates using a random effects model for both adjusted and unadjusted results. Two reviewers independently identified eligible studies and extracted data. Studies including adults with ARDS reporting a dead-space ventilation index and mortality.
MEDLINE, CENTRAL, and Google Scholar from inception to November 2022. In this systematic review and meta-analysis, we evaluated the ability of dead-space ventilation measures to predict mortality in patients with ARDS. However, whether the degree of dead-space ventilation is associated with outcomes is uncertain. Acute respiratory distress syndrome (ARDS) is associated with high ventilation-perfusion heterogeneity and dead-space ventilation.
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